When considered changing health care needs, nursing profession needs profession members who are researchers, creative, able to reaching knowledge, information producing and knowledgeable. Thus entrepreneurial and innovative concepts are most important for nurses. When evaluated in terms of nursing profession, entrepreneurship is part of making decisions to improve the skills of nurses and can be applied in business environment, besides this, it is part of decision making in the career planning and development process that nurses undertake. Entrepreneurial nurses can operate in the marketing, public and private sectors. On the basis of entrepreneurial in nursing.